Sugar Substitutes

Artificial Sweeteners

Saccharin

Saccharin (E954) is 200–700× sweeter than sugar and the oldest artificial sweetener.

Aspartame

Aspartame (E951) is 200× sweeter than sugar and a classic in diet drinks.

Acesulfame-K (Ace-K)

Acesulfame-K (E950) is 200× sweeter than sugar and almost always used in combination with other sweeteners.

Sucralose

Sucralose (E955) is 600× sweeter than sugar and made from real sugar.

Cyclamate

Cyclamate (E952) is 30× sweeter than sugar and is often combined with saccharin.

Neotame

Neotame (E961) is 7,000–13,000× sweeter than sugar and is structurally related to aspartame but more heat-resistant.

Sugar Alcohols (Polyols)

Erythritol

Erythritol (E968) provides only 0.2 kcal/g and is especially popular in low-carb cooking.

Xylitol

Xylitol (E967) is as sweet as sugar and best known from chewing gum and toothpaste.

Maltitol

Maltitol (E965) is 75–90% as sweet as sugar and often found in sugar-free chocolate.

Sorbitol & Mannitol

Sorbitol (E420) and mannitol (E421) are inexpensive, versatile sugar alcohols used widely in the food industry.

Isomalt

Isomalt (E953) is about 50% as sweet as sugar and the classic for hard candies and sugar decorations.

Lactitol

Lactitol (E966) is about 40% as sweet as sugar and is derived from milk sugar.

Plant-Based High-Intensity Sweeteners

Stevia

Stevia (E960) is 200–400× sweeter than sugar and is extracted from the stevia plant.

Monk Fruit

Monk fruit is 100–250× sweeter than sugar and comes from a Southeast Asian fruit.

Sweet Proteins

Thaumatin

Thaumatin (E957) is 2,000–3,000× sweeter than sugar and is extracted from the West African katemfe fruit (Thaumatococcus daniellii).

Brazzein & Monellin

Brazzein and monellin are new sweet proteins that have been available via fermentation since 2025/26.

Rare Sugars

Allulose

Allulose is a rare sugar that occurs naturally in small amounts in figs and raisins and is 70% as sweet as sugar.

Tagatose

Tagatose is a rare natural sugar derived from lactose and is about 90% as sweet as sugar.

Caloric Natural Sweeteners

Yacon Syrup

Yacon syrup is a prebiotic-rich sweetener from the yacon root with a very low glycemic index.

Recommendations for Beginners

PurposeRecommendation
Everyday / coffeeStevia or erythritol
BakingErythritol or sucralose
Chocolate & sweetsErythritol (check the label: maltitol raises blood sugar!)
Chewing gum / dental healthXylitol
Gut healthYacon syrup

Sweeteners Compared

The table summarises sweetness, energy value, glycemic index (GI), E number and EU approval status of the main sweeteners (as of October 2026). Sweetness is relative to table sugar (sucrose = 1). The kcal values for sugar alcohols are the EU's legal conversion factors.

SweetenerE numberSweetness (sugar = 1)kcal/gGI (glucose = 100)EU status
SaccharinE 954approx. 300–500negligible¹–²approved; ADI 9 mg/kg (EFSA 2024)
AspartameE 951approx. 200negligible¹–²approved; ADI 40 mg/kg; label must state "contains a source of phenylalanine"
Acesulfame KE 950approx. 200negligible¹–²approved; ADI 15 mg/kg (EFSA 2025)
SucraloseE 955approx. 600negligible¹–²approved; ADI 15 mg/kg (EFSA 2026)
CyclamateE 952approx. 30–50negligible¹–²approved; ADI 7 mg/kg; re-evaluation ongoing
ErythritolE 9680.6–0.800approved; ADI 0.5 g/kg (EFSA 2023)
XylitolE 9671.02.413approved; re-evaluation ongoing
MaltitolE 9650.92.435 (syrups 36–53)approved; re-evaluation ongoing
SorbitolE 4200.5–0.72.49approved; re-evaluation ongoing
IsomaltE 953approx. 0.45–0.652.49approved; re-evaluation ongoing
Steviol glycosides (stevia)E 960a–dapprox. 300negligible¹–²approved; ADI 4 mg/kg steviol equivalents (confirmed by EFSA 2024)
Monk fruit (mogrosides)–mogroside V approx. 250––²not approved as a sweetener; application under review
ThaumatinE 957approx. 2,000–3,000negligible¹–²approved
Allulose–approx. 0.7≤ 0.4 (FDA)–³not approved (novel food; EFSA 2025: safety not established)
Tagatose–approx. 0.9approx. 3 (EFSA estimate)3approved as a novel food (since 2005)
Yacon syrup––––³food; yacon root is no longer considered a novel food

¹ High-intensity sweeteners are used in such small amounts that their energy contribution is negligible. ² A GI can only be measured for foods with a meaningful carbohydrate content; high-intensity sweeteners provide practically no available carbohydrate. ³ No GI value from a reliable measurement is available. "–" means no established value. Neotame, lactitol, mannitol, brazzein and monellin are not listed because not all of their values are reliably documented.

Sources: Regulation (EU) No 1169/2011, Annex XIV (energy conversion factors); Livesey, Nutrition Research Reviews 2003 (GI of sugar alcohols); Atkinson et al., Diabetes Care 2008 (GI of tagatose); EFSA opinions on erythritol (2023), saccharin (2024), steviol glycosides (2024), acesulfame K (2025), sucralose (2026), aspartame (2013) and tagatose (2016); FDA guidance on allulose (2020).